Academic literature

textbooks, literature reviews, FOI requests and research articles

Year Published Title Publisher Author URL
2024 The gut-microbiota-brain axis: Focus on gut steroids Wiley Silvia Diviccaro, Silvia Giatti, Lucia Cioffi, Gabriela Chrostek, Roberto Cosimo Melcangi onlinelibrary.wiley.com
2024 Transcriptomic Profile of the Male Rat Hypothalamus and Nucleus Accumbens After Paroxetine Treatment and Withdrawal: Possible Causes of Sexual Dysfunction Springer Silvia Giatti, Lucia Cioffi, Silvia Diviccaro, Gabriela Chrostek, Rocco Piazza, Roberto Cosimo Melcangi link.springer.com
2024 Frequency of self-reported persistent post-treatment genital hypoesthesia among past antidepressant users: a cross-sectional survey of sexual and gender minority youth in Canada and the US Springer Yassie Pirani, J. Andrés Delgado-Ron, Pedro Marinho, Amit Gupta, Emily Grey, Sarah Watt, Kinnon R. MacKinnon, Travis Salway link.springer.com
2024 Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence Cambridge David Healy, Dee Mangin Cambridge.org
2024 Sexual Dysfunction Induced by Antidepressants Pharmaceuticals Rene Zeiss, Kathrin Malejko, Bernhard Connemann, Maximilian Gahr, Verena Durner, Heiko Graf https://doi.org/10.3390/ph17070826
2024 SSRI-Related Tardy Sexual Dysfunction The Primary Care Companion For CNS Disorders Ahmed Naguy, Bibi Alamiri Psychiatrist.com
2024 The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs Wiley Blackwell Mark Horowitz, David Taylor Google Books

PSSD mentioned on p. 69, 70, 98, 155.

2023 POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE Frontiers in Neuroendocrinology Silvia Giatti, Silvia Diviccaro, Lucia Cioffi, Roberto Cosimo Melcangi https://doi.org/10.1016/j.yfrne.2023.101114
2023 A clinical guide to rare male sexual disorders Nature Reviews Urology Murat Gül, Mikkel Fode, Ahmet Urkmez, Paolo Capogrosso, Marco Falcone, Selcuk Sarikaya, Ioannis Sokolakis, Afonso Morgado, Andrey Morozov, Maarten Albersen, Giorgio Ivan Russo, Ege Can Serefoglu https://doi.org/10.1038/s41585-023-00803-5
2023 Selective serotonin reuptake inhibitors, post-treatment sexual dysfunction and persistent genital arousal disorder: A systematic review Pharmacoepidemiology and Drug Safety Livio Tarchi, Giuseppe Pierpaolo Merola, Ottone Baccaredda-Boy, Francesca Arganini, Emanuele Cassioli, Eleonora Rossi, Mario Maggi, David S. Baldwin, Valdo Ricca, Giovanni Castellini https://doi.org/10.1002/pds.5653
2023 A clinical review of antidepressants, their sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome British Journal of Nursing Stephen Marks https://doi.org/10.12968/bjon.2023.32.14.678
2023 Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants Annals of General Psychiatry Joseph Ben-Sheetrit, Yehonathan Hermon, Shlomo Birkenfeld, Yehiel Gutman, Antonei B. Csoka, Paz Toren https://doi.org/10.1186/s12991-023-00447-0
2023 Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction - literature review Journal of Education, Health and Sport Eliasz Panek, Damian Jasłowski, Mateusz Rzeszutko, Przemysław Raczkiewicz, Dominika Panasiuk, Mateusz Skrętowicz, Patrycja Szponarowicz, Bartosz Snopkowski, Tomasz Korzec, Jakub Sosnowski https://doi.org/10.12775/jehs.2023.19.01.007
2023 The pathophysiology of Post SSRI Sexual Dysfunction – Lessons from a case study Biomedicine & Pharmacotherapy Samantha Klaas , Jessica Barbut Siva , Maarten Bak , Mark Govers , Rudy Schreiber https://doi.org/10.1016%2Fj.biopha.2022.114166
2022 British National Formulary, Edition 84 (BNF84) BMJ Group, and

Pharmaceutical Press

Pharmaceutical Press, the Royal Pharmaceutical Society's knowledge business https://www.pharmpress.com/product/9780857114327/bnf84
2022 Textbook of Rare Sexual Medicine Conditions Springer Yacov Reisman, Lior Lowenstein, Francesca Tripodi

https://doi.org/10.1007%2F978-3-030-98263-8_5

2022 Cutting the First Turf to Heal Post-SSRI Sexual Dysfunction: A Male Retrospective Cohort Study Medicines De Luca R, Bonanno M, Manuli A, Calabrò RS

https://www.mdpi.com/2305-6320/9/9/45/htm

2022 Screening and treatment of Post-Selective Serotonin Reuptake Inhibitors sexual dysfunctions Encephale Achour V, Masson M, Lancon C, Boyer L, Fond G

https://doi.org/10.1016/j.encep.2022.07.001

2022 Post-Selective Serotonin Reuptake Inhibitor Sexual Dysfunctions (PSSD): Clinical Experience with a Multimodal Approach Journal of Men’s Health Reisman Y, Jannini TB, Jannini EA

https://www.imrpress.com/journal/JOMH/18/8/10.31083/j.jomh1808165/htm

2022 Epistemology of the side effect: anecdote and evidence in the digital age BioSocieties Antoine Lentacker

https://doi.org/10.1057%2Fs41292-022-00293-5

2022 Paroxetine effects in adult male rat colon: Focus on steroidogenesis and microbiota Psychoneuroendocrinology Diviccaro S., Giatti S., Cioffi L., Falvo E., Piazza R., Caruso D., Melcangi R.C.

https://doi.org/10.1016/j.psyneuen.2022.105828

2022 Identification of a novel off-target of paroxetine: Possible role in sexual dysfunction induced by this SSRI antidepressant drug Journal of Molecular Structure Giatti S., Di Domizio A., Diviccaro S., Cioffi L., Marmorini I., Falvo E., Caruso D., Contini A., Melcangi R.C.

https://doi.org/10.1016/j.molstruc.2022.133690

2021 (German) Psychopharmaka absetzen? Warum, wann und wie? Urban&Fischer G Gründer

https://books.google.com/books?id=JEBNEAAAQBAJ&dq=pssd+ssri+%22derealisation%22&pg=PP1

2021 Psychiatry and Sexual Medicine: A Comprehensive Guide for Clinical Practitioners Springer Michal Lew-Starowicz,

Annamaria Giraldi,

Tillmann H. C. Krüger

https://doi.org/10.1007%2F978-3-030-52298-8

2021 Freedom of Information request on adverse sexual dysfunction reactions to SSRI use Medicines & Healthcare products

Regulatory Agency

Medicines & Healthcare products

Regulatory Agency

https://www.gov.uk/government/publications/freedom-of-information-responses-from-the-mhra-week-commencing-5-april-2021/freedom-of-information-request-on-adverse-sexual-dysfunction-reactions-to-ssri-use-foi-21-232

2021 Persistent sexual dysfunction after SSRI withdrawal: a scoping review and presentation of 86 cases from the Netherlands Expert Opinion on Drug Safety Chinchilla Alfaro K, van Hunsel F, Ekhart C

https://pubmed.ncbi.nlm.nih.gov/34791958/

2021 Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin International Journal of Risk & Safety in Medicine Healy D, Bahrick A, Bak M, Barbato A, Calabrò RS, Chubak BM, et al

https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf

2021 Charactarizing Post-SSRI sexual dysfunction and its impact on quality of life through an international online survey International Journal of Risk & Safety in Medicine Studt A, Gannon M, Orzel J, Vaughan A, Pearlman AM

https://pubmed.ncbi.nlm.nih.gov/34366299/

2021 Exposure to serotonin selective reuptake inhibitors or serotonin noradrenaline reuptake inhibitors and sexual dysfunction: Results from an online survey International Journal of Risk & Safety in Medicine Patacchini A, Cosci F

https://pubmed.ncbi.nlm.nih.gov/33579876/

2021 Effects of paroxetine treatment and its withdrawal on neurosteroidogenesis Psychoneuroendocrinology Giatti S, Diviccaro S, Cioffi L, Falvo E, Caruso D, Melcangi RC

https://pubmed.ncbi.nlm.nih.gov/34325207/

2020 Post-SSRI Sexual Dysfunction: Exploration of the Sexual Domains and Symptoms Master thesis (Clinical Psychology), Utrecht University Raj S

https://studenttheses.uu.nl/bitstream/handle/20.500.12932/37589/Raj%20%286816983%29%20thesis.pdf?sequence=1&isAllowed=y

2020 Post-SSRI sexual dysfunction (PSSD): Ten year retrospective chart review The Journal of Urology Waraich A, Clemons C, Ramirez R, Yih J, Goldstein S, Goldstein I

https://www.auajournals.org/doi/abs/10.1097/JU.0000000000000964.015

2020 Antidepressant-induced sexual dysfunction The Medical Journal of Australia Rothmore J

https://doi.org/10.5694/mja2.50522

2020 Post-SSRI sexual dysfunction The BMJ Reisman Y

https://www.bmj.com/content/368/bmj.m754

2020 Antidepressants and sexual dysfunction: a history Journal of the Royal Society of Medicine Healy D

https://journals.sagepub.com/doi/10.1177/0141076819899299

2020 Antidepressant Use During Development May Impair Women’s Sexual Desire in Adulthood The Journal of Sexual Medicine Lorenz TK

https://doi.org/10.1016/j.jsxm.2019.12.012

2020 A Paradigmatic Case of Postselective Serotonin Reuptake Inhibitors Sexual Dysfunction or Withdrawal After Discontinuation of Selective Serotonin Reuptake Inhibitors? Journal of Clinical Psychopharmacology Patacchini A, Cosci

https://doi.org/10.1097/jcp.0000000000001154

2019 European Medicines Agency's acknowledgement of persistent sexual dysfunction following the usage of SRI medication European Medicines Agency Pharmacovigilance Risk Assessment Committee (PRAC)

https://www.ema.europa.eu/en/documents/other/new-product-information-wording-extracts-prac-recommendations-signals-adopted-13-16-may-2019-prac_en.pdf#page=2

2019 Life after antidepressants: Does persisting sexual dysfunction influence quality of life? Master Thesis (Clinical Psychology), Utrecht University Lüning

https://dspace.library.uu.nl/handle/1874/395598

2019 Post-SSRI Sexual Dysfunction: A Bioelectric Mechanism? Bioelectricity Healy D, LaPalme J, Levin

https://www.liebertpub.com/doi/10.1089/bioe.2019.0010

2019 Are There Any Sex/Gender Differences in Post-Selective Serotonin Reuptake Inhibitors (SSRI) Sexual Dysfunction (PSDD)? Current Sexual Health Reports Reisman

https://doi.org/10.1007/s11930-019-00222-x

2019 Post-SSRI sexual dysfunction & other enduring sexual dysfunctions Epidemiology and Psychiatric Sciences Healy D

https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/postssri-sexual-dysfunction-other-enduring-sexual-dysfunctions/8343798C6C29E850661020EF0CEA8968/core-reader

2019 Post-SSRI sexual dysfunction: Patient experiences of engagement with healthcare professionals International Journal of Risk & Safety in Medicine Healy D, Le Noury J, Mangin D

https://doi.org/10.3233/JRS-191005

2019 Towards Improving Post-SSRI Sexual Dysfunction by Using Nutriceuticals: Lessons from a Case Study Journal of Sex & Marital Therapy Calabrò RS, De Luca R, Manuli A, Portaro S, Naro A, Quattrini F

https://doi.org/10.1080/0092623X.2018.1556755

2018 Citizen petition: Sexual side effects of SSRIs and SNRIs International Journal of Risk & Safety in Medicine Healy D

https://rxisk.org/wp-content/uploads/2018/06/JRS745-1.pdf

2018 Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases International Journal of Risk & Safety in Medicine Healy D, Le Noury J, Mangin D

https://rxisk.org/wp-content/uploads/2018/06/JRS744-2.pdf

2018 Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin? Endocrine Giatti S, Diviccaro S, Panzica G, Melcangi

https://doi.org/10.1007/s12020-018-1593-5

2018 Post-SSRI Sexual Dysfunction: Preclinical to Clinical Is It Fact or Fiction? Sexual Medicine Reviews Coskuner ER, Culha MG, Ozkan B, Kaleagasi EO

https://doi.org/10.1016/j.sxmr.2017.11.004

2017 Disfunción sexual persistente tras el tratamiento con inhibidores selectivos de la recaptación de serotonina: a propósito de un caso tras la retirada de paroxetina Psiquiatría Biológica Muquebil Ali Al Shaban Rodríguez OW, Álvarez de Morales Gómez-Moreno E, Fernández Fernández J, Fresno García C, del Mar Fernández Fernández M

https://doi.org/10.1016/j.psiq.2017.05.004

2017 Post-SSRI Sexual Dysfunction: A Literature Review Sexual Medicine Reviews Bala A, Tue Nguyen HM, Hellstrom WJG

https://doi.org/10.1016/j.sxmr.2017.07.002

2017 Sexual Consequences of Post-SSRI Syndrome Sexual Medicine Reviews Reisman Y

https://doi.org/10.1016/j.sxmr.2017.05.002

2016 Persistent sexual dysfunction after early exposure to SSRIs: Systematic review of animal studies International Journal of Risk & Safety in Medicine Simonsen AL, Danborg PB, Gøtzsche PC

https://doi.org/10.3233/JRS-160668

2015 Sexual dysfunction persisting after treatment with antidepressants (In Slovak) Psychiatria pre prax Vašečková B

https://www.solen.sk/casopisy/psychiatria-pre-prax/sexualne-dysfunkcie-pretrvavajuce-po-liecbe-antidepresivami

2015 Post-SSRI Sexual Dysfunction: Clinical Characterization and Preliminary Assessment of Contributory Factors and Dose-Response Relationship Journal of Clinical Psychopharmacology Ben-Sheetrit J, Aizenberg D, Csoka AB, Weizman A, Hermesh H

https://doi.org/10.1097/JCP.0000000000000300

2014 Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation: a case study and hypothesis about the role of transient receptor potential (TRP) ion channels European Journal of Pharmacology Waldinger MD, van Coevorden RS, Schweitzer DH, Georgiadis J

https://doi.org/10.1016/j.ejphar.2014.11.031

2014 One hundred and twenty cases of enduring sexual dysfunction following treatment International Journal of Risk & Safety in Medicine Hogan C, Le Noury J, Healy D, Mangin D

https://rxisk.org/wp-content/uploads/2015/02/2014-Hogan-SSRIs-and-PSSD.pdf

2014 Does sexual dysfunction persist upon discontinuation of selective serotonin reuptake inhibitors? (In Dutch) Tijdschrift voor Psychiatrie Ekhart GC, van Puijenbroek EP

http://www.tijdschriftvoorpsychiatrie.nl/en/issues/477/articles/10278

2013 DSM-5 American Psychiatric Association (Page 449) American Psychiatric Association

https://rxisk.org/wp-content/uploads/2017/07/DSM-PSSD.pdf#page=4

2013 The impact of persistent sexual side effects of selective serotonin reuptake inhibitors after discontinuing treatment: a qualitative study PhD (Doctor of Philosophy) thesis, University of Iowa Stinson RD

https://ir.uiowa.edu/etd/5061/

2012 SSRIs and persistent sexual dysfunction Netherlands Pharmacovigilance Centre Lareb

http://databankws.lareb.nl/Downloads/KWB_2012_3_SSRI.pdf

2009 Persistent sexual dysfunction in genitourinary medicine clinic attendees induced by selective serotonin reuptake inhibitors International Journal of STD & AIDS Farnsworth KD, Dinsmore WW

https://doi.org/10.1258/ijsa.2008.008402

2008 Sexual Side Effects of Antidepressant Medications: An Informed Consent Accountability Gap Journal of Contemporary Psychotherapy Bahrick AS, Harris MM

https://www.researchgate.net/publication/225332168_Sexual_Side_Effects_of_Antidepressant_Medications_An_Informed_Consent_Accountability_Gap

2008 Persistent Sexual Side Effects after Discontinuation of Psychotropic Medications Primary Psychiatry Kauffman RP

Persistent sexual side effects after discontinuation of psychotropic medications

2008 Persistence of Sexual Dysfunction Side Effects after Discontinuation of Antidepressant Medications: Emerging Evidence The Open Psychology Journal Bahrick AS

https://benthamopen.com/contents/pdf/TOPSYJ/TOPSYJ-1-42.pdf

2008 Persistent sexual dysfunction after discontinuation of selective serotonin reuptake inhibitors The Journal of Sexual Medicine Csoka AB, Bahrick A, Mehtonen OP

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1743-6109.2007.00630.x

2007 Prolonged Post-Treatment Genital Anesthesia and Sexual Dysfunction Following Discontinuation of Citalopram and the Atypical Antidepressant Nefazodone The Open Women’s Health Journal Kauffman RP, Murdock A

https://benthamopen.com/contents/pdf/TOWHJ/TOWHJ-1-1.pdf

2006 Post SSRI sexual dysfunction American Society for the Advancement of Pharmacotherapy Tablet Bahrick AS

https://www.researchgate.net/publication/236587031_Post_SSRI_Sexual_Dysfunction

2006 Persistent sexual side effects after SSRI discontinuation Psychotherapy and Psychosomatics Csoka AB, Shipko S

https://doi.org/10.1159/000091777

2006 Genital anaesthesia persisting six years after sertraline discontinuation Journal of Sex & Marital Therapy Bolton JM, Sareen J, Reiss JP

https://doi.org/10.1080/00926230600666410